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Commentary
Online Published: 26 Feb 2025
 


Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC

Nayyar Rubab, Warda Ahmed.


Abstract
Radioactive iodine therapy is non-invasive, well established and effective treatment for hyperthyroidism. However, there are concerns about its potential to cause thyroid cancer when used for benign thyroid diseases. While studies show mixed results, our observations indicate that the risk of cancer after RAI therapy for benign conditions is very low, given that pre-therapy nodules have been confirmed as benign either through sonographic examination or fine-needle aspiration cytology (FNAC). This perspective is grounded because the iodine dose used for benign thyroid diseases is low and causes cell death rather than cancer.

Key words: Benign thyroid disorders, Radioactive iodine therapy, Thyroid CA risk, sonographic and cytological evaluation.


 
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Pubmed Style

Rubab N, Ahmed W. Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. Pak J Nucl Med. 2024; 14(2): 41-44. doi:10.24911/PJNMed.175-1715919219

Web Style

Rubab N, Ahmed W. Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. https://www.pjnmed.com/?mno=202035 [Access: June 28, 2026]. doi:10.24911/PJNMed.175-1715919219

AMA (American Medical Association) Style

Rubab N, Ahmed W. Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. Pak J Nucl Med. 2024; 14(2): 41-44. doi:10.24911/PJNMed.175-1715919219


Vancouver/ICMJE Style

Rubab N, Ahmed W. Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. Pak J Nucl Med. (2024), [cited June 28, 2026]; 14(2): 41-44. doi:10.24911/PJNMed.175-1715919219


Harvard Style

Rubab, N. & Ahmed, . W. (2024) Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. Pak J Nucl Med, 14 (2), 41-44. doi:10.24911/PJNMed.175-1715919219


Turabian Style

Rubab, Nayyar, and Warda Ahmed. 2024. Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. Pakistan Journal of Nuclear Medicine, 14 (2), 41-44. doi:10.24911/PJNMed.175-1715919219


Chicago Style

Rubab, Nayyar, and Warda Ahmed. "Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC." Pakistan Journal of Nuclear Medicine 14 (2024), 41-44. doi:10.24911/PJNMed.175-1715919219


MLA (The Modern Language Association) Style

Rubab, Nayyar, and Warda Ahmed. "Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC." Pakistan Journal of Nuclear Medicine 14.2 (2024), 41-44. Print. doi:10.24911/PJNMed.175-1715919219


APA (American Psychological Association) Style

Rubab, N. & Ahmed, . W. (2024) Morphological changes in Benign Thyroid Nodules after Radioactive Iodine Therapy: A Focus on Ultrasound and FNAC. Pakistan Journal of Nuclear Medicine, 14 (2), 41-44. doi:10.24911/PJNMed.175-1715919219




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