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Case Report 


Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated <sup>99m</sup>Tc- DMSA (V)<br>

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah.


Abstract
Medullary thyroid carcinoma (MTC) is a distinct C-cell tumour of the thyroid gland that produces calcitonin in high quantities. Various imaging techniques are available in nuclear medicine to image MTC which include <sup>131</sup>I-MIBG and somatostatin receptor imaging agent <sup>111</sup>In-Octreotide.Due to the nonavailability of these agents in Pakistan, we tried using locally prepared <sup>99m</sup>Tc-labelled pentavalent dimercaptosuccinic acid (<sup>99m</sup>Tc(V)-DMSA) in a patient suspected of advanced MTC. CT with contrast could not be performed in this patient due to raised serum urea and creatinine levels indicating renal impairment. <sup>99m</sup>Tc(V)-DMSA was prepared by modification of a locally formulated kit of renal DMSA. Significant accumulation of the tracer was seen in the gross disease present in the neck and mediastinum. The resolution and good physical characteristics of <sup>99m</sup>Tc(V)-DMSA make it a useful agent for MTC imaging, where other modalities are not available.


 
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How to Cite this Article
Pubmed Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. Pak J Nucl Med. 2013; 3(1): 73-77.

Web Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. https://www.pjnmed.com/?mno=284583 [Access: February 28, 2024].

AMA (American Medical Association) Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. Pak J Nucl Med. 2013; 3(1): 73-77.


Vancouver/ICMJE Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. Pak J Nucl Med. (2013), [cited February 28, 2024]; 3(1): 73-77.


Harvard Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah (2013) Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. Pak J Nucl Med, 3 (1), 73-77.


Turabian Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. 2013. Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. Pakistan Journal of Nuclear Medicine, 3 (1), 73-77.


Chicago Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. "Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
." Pakistan Journal of Nuclear Medicine 3 (2013), 73-77.


MLA (The Modern Language Association) Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah. "Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
." Pakistan Journal of Nuclear Medicine 3.1 (2013), 73-77. Print.


APA (American Psychological Association) Style

Aakif Ullah Khan, Hameedullah, Aamir Bahadur, Muhammad Rauf Khattak, Abdus Saeed Shah (2013) Mediastinal spread of medullary thyroid carcinoma imaged by locally formulated 99mTc- DMSA (V)
. Pakistan Journal of Nuclear Medicine, 3 (1), 73-77.




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