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Case Report 


Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report

Aakif U Khan, Hameedullah, Abdul Saeed Shah, Muhammad Rauf Khattak.


Abstract
Radiosynoviorthesis (RSO) is an attractive alternative to surgical synovectomy for controlling symptoms of rheumatoid arthritis and many other chronic proliferative joint diseases. The procedure is not widely used in our country because of the non-availability of suitable radionuclides and radiopharmaceuticals. The production of rhenium-188 (188Re) from 188W/188Re generator and by labelling it with particles of appropriate size, has a promise to offer. We labelled 188Re with tin colloid and analyzed its biodistribution and clinical efficacy after injecting it to a patient with recurrent pigmented villonodular synovitis. Gamma camera imaging performed after 1, 24 and 48 hrs showed no leakage of the radiopharmaceutical from the injected joint. The clinical outcome of this study was also excellent, which suggests that 188Re labelled tin colloid is a potentially effective radiopharmaceutical for recurrent PVNS and can be used for other chronic inflammatory joint diseases.


 
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How to Cite this Article
Pubmed Style

Khan AU, Hameedullah , Shah AS, Khattak MR. Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. Pak J Nucl Med. 2016; 6(1): 42-47.

Web Style

Khan AU, Hameedullah , Shah AS, Khattak MR. Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. https://www.pjnmed.com/?mno=284586 [Access: June 29, 2026].

AMA (American Medical Association) Style

Khan AU, Hameedullah , Shah AS, Khattak MR. Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. Pak J Nucl Med. 2016; 6(1): 42-47.


Vancouver/ICMJE Style

Khan AU, Hameedullah , Shah AS, Khattak MR. Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. Pak J Nucl Med. (2016), [cited June 29, 2026]; 6(1): 42-47.


Harvard Style

Khan, A. U., Hameedullah, ., Shah, . A. S. & Khattak, . M. R. (2016) Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. Pak J Nucl Med, 6 (1), 42-47.


Turabian Style

Khan, Aakif U, Hameedullah, Abdul Saeed Shah, and Muhammad Rauf Khattak. 2016. Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. Pakistan Journal of Nuclear Medicine, 6 (1), 42-47.


Chicago Style

Khan, Aakif U, Hameedullah, Abdul Saeed Shah, and Muhammad Rauf Khattak. "Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report." Pakistan Journal of Nuclear Medicine 6 (2016), 42-47.


MLA (The Modern Language Association) Style

Khan, Aakif U, Hameedullah, Abdul Saeed Shah, and Muhammad Rauf Khattak. "Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report." Pakistan Journal of Nuclear Medicine 6.1 (2016), 42-47. Print.


APA (American Psychological Association) Style

Khan, A. U., Hameedullah, ., Shah, . A. S. & Khattak, . M. R. (2016) Radiosynoviorthesis in pigmented villonodular synovitis using Re-188 labelled tin colloid: a case report. Pakistan Journal of Nuclear Medicine, 6 (1), 42-47.




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