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99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies

Muhammad Inamullah, Mujahid Khalid Ali, Tariq Mahmood Mirza, Muhammad Omair Riaz.


Abstract
Aims: This retrospective study aimed at determining the prevalence of biliary atresia in children presenting with persistent neonatal jaundice by technetium-99m labelled hepatoimino diacetic acid (99mTc-HIDA) scintigraphy. The results were compared with those from similar studies conducted in Pakistan, South East Asia & internationally.

Methods: The study was conducted at Nuclear Medicine Centre, Armed Forces Institute of Pathology, Rawalpindi, from June 2010 to December 2012. A total of 80 patients with persistent neonatal jaundice were included in the study with 54 males & 26 females in a ratio of about 2 to 1. Main outcome measure was demonstration of biliary atresia on technetium-99m labelled hepatoiminodiacetic acid (99mTc-HIDA) scan.

Results: Patients with a clinical diagnosis of persistent neonatal jaundice were included in the study. The mean age for males and females at presentation was 224 & 122 days respectively. Biliary atresia was diagnosed in 45 patients with 28 being male and 17 female patients respectively.

Conclusion: A significant percentage of patients (56.25%) presenting with persistent neonatal jaundice are found to have biliary atresia on scintigraphic evaluation.


 
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How to Cite this Article
Pubmed Style

Inamullah M, Ali MK, Mirza TM, Riaz MO. 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. Pak J Nucl Med. 2014; 4(1): 40-45.

Web Style

Inamullah M, Ali MK, Mirza TM, Riaz MO. 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. https://www.pjnmed.com/?mno=284628 [Access: July 03, 2026].

AMA (American Medical Association) Style

Inamullah M, Ali MK, Mirza TM, Riaz MO. 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. Pak J Nucl Med. 2014; 4(1): 40-45.


Vancouver/ICMJE Style

Inamullah M, Ali MK, Mirza TM, Riaz MO. 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. Pak J Nucl Med. (2014), [cited July 03, 2026]; 4(1): 40-45.


Harvard Style

Inamullah, M., Ali, . M. K., Mirza, . T. M. & Riaz, . M. O. (2014) 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. Pak J Nucl Med, 4 (1), 40-45.


Turabian Style

Inamullah, Muhammad, Mujahid Khalid Ali, Tariq Mahmood Mirza, and Muhammad Omair Riaz. 2014. 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. Pakistan Journal of Nuclear Medicine, 4 (1), 40-45.


Chicago Style

Inamullah, Muhammad, Mujahid Khalid Ali, Tariq Mahmood Mirza, and Muhammad Omair Riaz. "99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies." Pakistan Journal of Nuclear Medicine 4 (2014), 40-45.


MLA (The Modern Language Association) Style

Inamullah, Muhammad, Mujahid Khalid Ali, Tariq Mahmood Mirza, and Muhammad Omair Riaz. "99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies." Pakistan Journal of Nuclear Medicine 4.1 (2014), 40-45. Print.


APA (American Psychological Association) Style

Inamullah, M., Ali, . M. K., Mirza, . T. M. & Riaz, . M. O. (2014) 99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. Pakistan Journal of Nuclear Medicine, 4 (1), 40-45.




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