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Original Article 


Thyroid retarding effects of dimethyl sulfoxide

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood.


Abstract
Aims: The study was aimed to determine the antithyroid activity of Dimethyl sulfoxide, a universal solvent. <br><br> Methods: The antithyroid effects of DMSO were investigated in vivo in male Wistar rats. <br><br> Results: Daily dose administration of 0.4 mL/100g to the animals significantly decreased the free triidothyronine and thyroxine levels and increased the thyroid stimulating hormone levels. The animals were afterwards dissected and thyroids were studied under microscope which revealed modifications at cellular level. Thyroid weight per 100 grams of bodv weight for the animals treated with DMSO were also found higher than control animals. <br><br> Conclusion: DMSO demosntrated moderate antithyroid activity in rats.


 
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How to Cite this Article
Pubmed Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. Thyroid retarding effects of dimethyl sulfoxide. Pak J Nucl Med. 2012; 2(1): 33-37.

Web Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. Thyroid retarding effects of dimethyl sulfoxide. https://www.pjnmed.com/?mno=284651 [Access: February 27, 2024].

AMA (American Medical Association) Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. Thyroid retarding effects of dimethyl sulfoxide. Pak J Nucl Med. 2012; 2(1): 33-37.


Vancouver/ICMJE Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. Thyroid retarding effects of dimethyl sulfoxide. Pak J Nucl Med. (2012), [cited February 27, 2024]; 2(1): 33-37.


Harvard Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood (2012) Thyroid retarding effects of dimethyl sulfoxide. Pak J Nucl Med, 2 (1), 33-37.


Turabian Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. 2012. Thyroid retarding effects of dimethyl sulfoxide. Pakistan Journal of Nuclear Medicine, 2 (1), 33-37.


Chicago Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. "Thyroid retarding effects of dimethyl sulfoxide." Pakistan Journal of Nuclear Medicine 2 (2012), 33-37.


MLA (The Modern Language Association) Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood. "Thyroid retarding effects of dimethyl sulfoxide." Pakistan Journal of Nuclear Medicine 2.1 (2012), 33-37. Print.


APA (American Psychological Association) Style

Ismat Fatima, Munawar Ali Munawar, Affia, Tasneem, Nasir Mehmood (2012) Thyroid retarding effects of dimethyl sulfoxide. Pakistan Journal of Nuclear Medicine, 2 (1), 33-37.




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