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Review Article
Online Published: 09 Sep 2026
 


Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings

Hamza Zia, Zainab Tariq, Muhammad Numair Younis, Sadaf Abdul Qadir, Tariq Mahmood Mirza.


Abstract
American Thyroid Association (ATA) guidelines for differentiated thyroid cancer have significantly changed between 2015 and 2025. The 2015 ATA guidelines recommended selective but relatively extensive use of radioactive Iodine (RAI) for low-risk and intermediate-risk patients as adjuvant treatment, residual ablation, and post-operative thyroglobulin monitoring. Accordingly, more radiation isolation facilities for patients, contamination control procedures, and radiation surveillance systems were required.
The revised ATA Guidelines and Clinical Updates for Thyroid Cancer Management, 2025, presented a more conservative and risk adaptive approach, which emphasizes personalized treatment, avoidance of unnecessary RAI administration in low-risk patients, and selection of intermediate-risk patients depending on treatment benefits. These changes are expected to reduce radiation exposure to patients, occupational exposure, and radioactive waste generation, with corresponding implications for radiation protection techniques and protocols.
This commentary analyzes how the radiation protection principles and methods are impacted by this shift in ATA guidelines. It particularly examines outpatient RAI administration, patient dose optimization, requirements for radiation isolation, occupational exposure, and radioactive waste management. Furthermore, how these updated guidelines align more closely with the core radiation protection principles of justification, optimization, and As Low As Reasonably Achievable (ALARA).

Key words: Differentiated Thyroid Cancer, ATA 2015, ATA 2025, RAI, Radioactive Iodine, Radiation Protection, Nuclear Medicine, I-131 Therapy, ALARA, Radiation Safety, Outpatient Radioiodine Therapy.


 
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How to Cite this Article
Pubmed Style

Zia H, Tariq Z, Younis MN, Qadir SA, Mirza TM. Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. Pak J Nucl Med. 2026; 16(1): 38-41. doi:10.24911/PJNMed.175-1780312233

Web Style

Zia H, Tariq Z, Younis MN, Qadir SA, Mirza TM. Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. https://www.pjnmed.com/?mno=322847 [Access: September 19, 2026]. doi:10.24911/PJNMed.175-1780312233

AMA (American Medical Association) Style

Zia H, Tariq Z, Younis MN, Qadir SA, Mirza TM. Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. Pak J Nucl Med. 2026; 16(1): 38-41. doi:10.24911/PJNMed.175-1780312233


Vancouver/ICMJE Style

Zia H, Tariq Z, Younis MN, Qadir SA, Mirza TM. Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. Pak J Nucl Med. (2026), [cited September 19, 2026]; 16(1): 38-41. doi:10.24911/PJNMed.175-1780312233


Harvard Style

Zia, H., Tariq, . Z., Younis, . M. N., Qadir, . S. A. & Mirza, . T. M. (2026) Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. Pak J Nucl Med, 16 (1), 38-41. doi:10.24911/PJNMed.175-1780312233


Turabian Style

Zia, Hamza, Zainab Tariq, Muhammad Numair Younis, Sadaf Abdul Qadir, and Tariq Mahmood Mirza. 2026. Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. Pakistan Journal of Nuclear Medicine, 16 (1), 38-41. doi:10.24911/PJNMed.175-1780312233


Chicago Style

Zia, Hamza, Zainab Tariq, Muhammad Numair Younis, Sadaf Abdul Qadir, and Tariq Mahmood Mirza. "Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings." Pakistan Journal of Nuclear Medicine 16 (2026), 38-41. doi:10.24911/PJNMed.175-1780312233


MLA (The Modern Language Association) Style

Zia, Hamza, Zainab Tariq, Muhammad Numair Younis, Sadaf Abdul Qadir, and Tariq Mahmood Mirza. "Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings." Pakistan Journal of Nuclear Medicine 16.1 (2026), 38-41. Print. doi:10.24911/PJNMed.175-1780312233


APA (American Psychological Association) Style

Zia, H., Tariq, . Z., Younis, . M. N., Qadir, . S. A. & Mirza, . T. M. (2026) Impact of ATA 2025 guidelines of thyroid cancer management on radiation safety procedures in clinical settings. Pakistan Journal of Nuclear Medicine, 16 (1), 38-41. doi:10.24911/PJNMed.175-1780312233




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